Vitamin D3 and Omega-3 Supplementation Reduce Incident Autoimmune Disease
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Vitamin D3 and Omega-3 Supplementation Reduce Incident Autoimmune Disease

Vitamin D3 and Omega-3 Supplementation Reduce Incident Autoimmune Disease

•Vitamin D3 and omega-3 fatty acid supplementation reduces the risk of developing autoimmune disease by 25% to 30% in older adults. •Incident autoimmune disease was reported among 117 participants in the vitamin D3 group and 150 participants in the placebo group (hazard ratio [HR], 0.78; 95% CI, 0.61-1.00; =.04); confirmed autoimmune disease was also diagnosed in 123 participants in the omega-3 group and 144 participants in the placebo group (HR, 0.85; 95% CI, 0.67-1.09). Excluding the first 2 years, the HRs for the primary outcome were 0.61 (0.43-0.86; n=137) and 0.90 (0.64-1.26) in the vitamin D3 and omega-3 groups, respectively.

Read More: Hahn J, Cook N, Alexander E, Friedman S, Bubes V, Walter J, Kotler G, Lee I, Manson J, Costenbader K. Vitamin D and marine n-3 fatty acid supplementation and prevention of autoimmune disease in the VITAL randomized controlled trial. Presented at: ACR Convergence 2021; November 3-10, 2021. Abstract 0957

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